Issue 3, 2016

The chemistry and biology of guanidine natural products

Abstract

Covering: 2012 to 2014. Previous review: Nat. Prod. Rep., 2012, 29, 1382

The present review discusses the isolation, structure determination, synthesis, biosynthesis and biological activities of secondary metabolites bearing a guanidine group. Topics include non-ribosomal peptides, alkaloids, guanidine-bearing terpenes, polyketides and shikimic acid derivatives from natural sources. A critical analysis of some yet underdeveloped aspects of guanidine metabolites is also presented.

Graphical abstract: The chemistry and biology of guanidine natural products

Article information

Article type
Review Article
Submitted
01 Sep 2015
First published
22 Dec 2015

Nat. Prod. Rep., 2016,33, 456-490

Author version available

The chemistry and biology of guanidine natural products

R. G. S. Berlinck and S. Romminger, Nat. Prod. Rep., 2016, 33, 456 DOI: 10.1039/C5NP00108K

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