Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 13, 2016
Previous Article Next Article

Personalized nutrition diagnostics at the point-of-need

Author affiliations

Abstract

Micronutrient deficiency is widespread and negatively impacts morbidity, mortality, and quality of life globally. On-going advancements in nutritional biomarker discovery are enabling objective and accurate assessment of an individual's micronutrient and broader nutritional status. The vast majority of such assessment however still needs to be conducted in traditional centralized laboratory facilities which are not readily accessible in terms of cost and time in both the developed and developing countries. Lab-on-a-chip (LOC) technologies are enabling an increasing number of biochemical reactions at the point-of-need (PON) settings, and can significantly improve the current predicament in nutrition diagnostics by allowing rapid evaluation of one's nutritional status and providing an easy feedback mechanism for tracking changes in diet or supplementation. We believe that nutrition diagnostics represents a particularly appealing opportunity over other PON applications for two reasons: (1) healthy ranges for many micronutrients are well defined which allows for an unbiased diagnosis, and (2) many deficiencies can be reversed through changes in diet or supplementation before they become severe. In this paper, we provide background on nutritional biomarkers used in nutrition diagnostics and review the emerging technologies that exploit them at the point-of-need.

Graphical abstract: Personalized nutrition diagnostics at the point-of-need

Back to tab navigation

Article information


Submitted
24 Mar 2016
Accepted
31 May 2016
First published
31 May 2016

Lab Chip, 2016,16, 2408-2417
Article type
Frontier

Personalized nutrition diagnostics at the point-of-need

S. Lee, B. Srinivasan, S. Vemulapati, S. Mehta and D. Erickson, Lab Chip, 2016, 16, 2408
DOI: 10.1039/C6LC00393A

Social activity

Search articles by author

Spotlight

Advertisements