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Issue 11, 2016

Embroidered electrochemical sensors for biomolecular detection

Author affiliations

Abstract

Electrochemical sensors are powerful analytical tools which possess the capacity for rapid detection of biomarkers in clinical specimens. While most electrochemical sensors are fabricated on rigid substrates, there is a growing need for sensors that can be manufactured on inexpensive and flexible materials. Here, we present a unique embroidered electrochemical sensor that is capable of quantitative analytical measurements using raw biofluid samples. Conductive threads immobilized with enzyme probes were generated using a simple and robust fabrication process and used to fabricate flexible, mechanically robust electrodes on textiles. For proof of concept, measurements were performed to detect glucose and lactate in buffer and whole blood samples, which exhibited excellent specificity and accuracy. We also demonstrate that our embroidered biosensor can be readily fabricated in two-dimensional (2D) arrays for multiplexed measurements. Lastly, we show that this biosensor exhibits good resiliency against mechanical stress and superior repeatability, which are important requirements for flexible sensor platforms.

Graphical abstract: Embroidered electrochemical sensors for biomolecular detection

Supplementary files

Article information


Submitted
03 Mar 2016
Accepted
29 Apr 2016
First published
29 Apr 2016

Lab Chip, 2016,16, 2093-2098
Article type
Paper

Embroidered electrochemical sensors for biomolecular detection

X. Liu and P. B. Lillehoj, Lab Chip, 2016, 16, 2093 DOI: 10.1039/C6LC00307A

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