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Issue 99, 2016
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Multiplex miRNA assay using lanthanide-tagged probes and the duplex-specific nuclease amplification strategy

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Abstract

A multiplex ICP-MS-based miRNA assay with duplex-specific nuclease amplification using bifunctional oligonucleotide probes was proposed. A multiplex assay of miR-141, let-7d, and miR-21 could be achieved simultaneously.

Graphical abstract: Multiplex miRNA assay using lanthanide-tagged probes and the duplex-specific nuclease amplification strategy

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Supplementary files

Article information


Submitted
16 Oct 2016
Accepted
18 Nov 2016
First published
18 Nov 2016

Chem. Commun., 2016,52, 14310-14313
Article type
Communication

Multiplex miRNA assay using lanthanide-tagged probes and the duplex-specific nuclease amplification strategy

S. Zhang, R. Liu, Z. Xing, S. Zhang and X. Zhang, Chem. Commun., 2016, 52, 14310
DOI: 10.1039/C6CC08334J

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