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The dangerously high power levels required for fast ASAP-HSQC and ASAP-HMQC experiments are mitigated by employing EXACT NMR. The utility of this technique is demonstrated by application of the EXACT ASAP-HSQC to chemical reaction monitoring, accelerating data acquisition by up to 2 orders of magnitude – providing evidence of it's value in fast quantitative NMR processes.

Graphical abstract: Rapid and safe ASAP acquisition with EXACT NMR

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