A series of novel phosphinate-based dyes displaying near-infrared fluorescence (NIR) are reported. These dyes exhibit remarkable photostability and brightness. The phosphinate functionality is leveraged as an additional reactive handle in order to tune cell permeability as well as provide a proof-of-principle for a self-reporting small molecule delivery vehicle.
X. Zhou, R. Lai, J. R. Beck, H. Li and C. I. Stains, Chem. Commun., 2016, 52, 12290 DOI: 10.1039/C6CC05717A
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