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Issue 53, 2016
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“Smart” gold nanoparticles for photoacoustic imaging: an imaging contrast agent responsive to the cancer microenvironment and signal amplification via pH-induced aggregation

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Abstract

‘Smart’ gold nanoparticles can respond to mild acidic environments, rapidly form aggregates, and shift the absorption to red and near-infrared. They were used as a photoacoustic imaging agent responsive to the cancer microenvironment, and have demonstrated the cancer-specific accumulation at the cellular level and an amplified signal which is twice higher than the control in vivo.

Graphical abstract: “Smart” gold nanoparticles for photoacoustic imaging: an imaging contrast agent responsive to the cancer microenvironment and signal amplification via pH-induced aggregation

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Article information


Submitted
13 Apr 2016
Accepted
06 Jun 2016
First published
13 Jun 2016

Chem. Commun., 2016,52, 8287-8290
Article type
Communication

“Smart” gold nanoparticles for photoacoustic imaging: an imaging contrast agent responsive to the cancer microenvironment and signal amplification via pH-induced aggregation

J. Song, J. Kim, S. Hwang, M. Jeon, S. Jeong, C. Kim and S. Kim, Chem. Commun., 2016, 52, 8287
DOI: 10.1039/C6CC03100E

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