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Issue 59, 2016
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Observation of intracellular interactions between DNA origami and lysosomes by the fluorescence localization method

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Abstract

We obtained the fluorescence localization images of tube DNA origami nanostructures in NIH 3T3 cells for the first time. The fluorescence localization images of tube DNA origami nanostructures and TIRF images of lysosomes were combined and they revealed the detailed interactions between the two structures. Quantitative analysis illustrated that the tube origami can be captured as well as degraded by lysosomes with time.

Graphical abstract: Observation of intracellular interactions between DNA origami and lysosomes by the fluorescence localization method

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Publication details

The article was received on 18 Jan 2016, accepted on 19 Jun 2016 and first published on 20 Jun 2016


Article type: Communication
DOI: 10.1039/C6CC00484A
Citation: Chem. Commun., 2016,52, 9240-9242

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    Observation of intracellular interactions between DNA origami and lysosomes by the fluorescence localization method

    M. Fu, L. Dai, Q. Jiang, Y. Tang, X. Zhang, B. Ding and J. Li, Chem. Commun., 2016, 52, 9240
    DOI: 10.1039/C6CC00484A

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