Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 58, 2016
Previous Article Next Article

Development of a disaggregation-induced emission probe for the detection of RecA inteins from Mycobacterium tuberculosis

Author affiliations

Abstract

A fluorescent sensor – InR – with disaggregation-induced emission (DIE) characteristics has been developed for the label free detection of RecA inteins from Mycobacterium tuberculosis. Mechanistic studies demonstrate that InR binds at a hydrophobic pocket of RecA inteins, which is constituted by Gly435, Glu434, Arg405 and Arg 7, resulting in the disaggregation and recovery of its fluorescence.

Graphical abstract: Development of a disaggregation-induced emission probe for the detection of RecA inteins from Mycobacterium tuberculosis

Back to tab navigation

Supplementary files

Article information


Submitted
16 Jan 2016
Accepted
19 Feb 2016
First published
19 Feb 2016

Chem. Commun., 2016,52, 9086-9088
Article type
Communication

Development of a disaggregation-induced emission probe for the detection of RecA inteins from Mycobacterium tuberculosis

X. Li, H. Jiang, Z. Luo, Y. Chang and L. Zhang, Chem. Commun., 2016, 52, 9086
DOI: 10.1039/C6CC00439C

Social activity

Search articles by author

Spotlight

Advertisements