Issue 32, 2016
From the journal:

Chemical Communications

Proximity ligation-induced assembly of DNAzymes for simple and cost-effective colourimetric detection of proteins with high sensitivity†

Luming Wei,a   Xiaoying Wang,b   Dan Wu,a   Chao Li,a   Yongmei Yinb  and  Genxi Li*ac  

* Corresponding authors

a State Key Laboratory of Pharmaceutical Biotechnology and Collaborative Innovation Center of Chemistry for Life Sciences, Department of Biochemistry, Nanjing University, Nanjing 210093, P. R. China
E-mail: genxili@nju.edu.cn
Fax: +86 25 83592510

b Department of Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, P. R. China

c Laboratory of Biosensing Technology, School of Life Sciences, Shanghai University, Shanghai 200444, P. R. China

Abstract

A novel colourimetric method for protein assays is proposed based on proximity ligation induced assembly of Mg2+-dependent DNAzymes, which may offer simple, cost-effective, sensitive and selective detection of the target protein.

Graphical abstract: Proximity ligation-induced assembly of DNAzymes for simple and cost-effective colourimetric detection of proteins with high sensitivity

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C6CC00205F
Article type
Communication
Submitted
09 Jan 2016
Accepted
18 Mar 2016
First published
18 Mar 2016

Chem. Commun., 2016,52, 5633-5636

Permissions

Request permissions

Proximity ligation-induced assembly of DNAzymes for simple and cost-effective colourimetric detection of proteins with high sensitivity

L. Wei, X. Wang, D. Wu, C. Li, Y. Yin and G. Li, Chem. Commun., 2016, 52, 5633 DOI: 10.1039/C6CC00205F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements