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Issue 58, 2016
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A highly selective fluorogenic probe for the detection and in vivo imaging of Cu/Zn superoxide dismutase

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Abstract

Copper/zinc superoxide dismutase (Cu/Zn SOD) is an essential enzyme that protects tissue from oxidative damage. Herein we report the first fluorogenic probe (SODO) for the detection and in vivo imaging of Cu/Zn SOD. SODO represents a unique chemical probe for translational imaging studies of Cu/Zn SOD in inflammatory disorders.

Graphical abstract: A highly selective fluorogenic probe for the detection and in vivo imaging of Cu/Zn superoxide dismutase

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Publication details

The article was received on 05 Jan 2016, accepted on 25 Feb 2016 and first published on 25 Feb 2016


Article type: Communication
DOI: 10.1039/C6CC00095A
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Chem. Commun., 2016,52, 9093-9096
  • Open access: Creative Commons BY license
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    A highly selective fluorogenic probe for the detection and in vivo imaging of Cu/Zn superoxide dismutase

    L. Zhang, J. C. Er, H. Jiang, X. Li, Z. Luo, T. Ramezani, Y. Feng, M. K. Tang, Y. Chang and M. Vendrell, Chem. Commun., 2016, 52, 9093
    DOI: 10.1039/C6CC00095A

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