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Issue 58, 2016
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A highly selective fluorogenic probe for the detection and in vivo imaging of Cu/Zn superoxide dismutase

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Abstract

Copper/zinc superoxide dismutase (Cu/Zn SOD) is an essential enzyme that protects tissue from oxidative damage. Herein we report the first fluorogenic probe (SODO) for the detection and in vivo imaging of Cu/Zn SOD. SODO represents a unique chemical probe for translational imaging studies of Cu/Zn SOD in inflammatory disorders.

Graphical abstract: A highly selective fluorogenic probe for the detection and in vivo imaging of Cu/Zn superoxide dismutase

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Supplementary files

Article information


Submitted
05 Jan 2016
Accepted
25 Feb 2016
First published
25 Feb 2016

This article is Open Access

Chem. Commun., 2016,52, 9093-9096
Article type
Communication
Author version available

A highly selective fluorogenic probe for the detection and in vivo imaging of Cu/Zn superoxide dismutase

L. Zhang, J. C. Er, H. Jiang, X. Li, Z. Luo, T. Ramezani, Y. Feng, M. K. Tang, Y. Chang and M. Vendrell, Chem. Commun., 2016, 52, 9093
DOI: 10.1039/C6CC00095A

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