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Issue 35, 2016
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Design of a hydrophobic tripeptide that self-assembles into amphiphilic superstructures forming a hydrogel biomaterial

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Abstract

We report the rational design of a heterochiral hydrophobic tripeptide self-assembling into amphiphilic D-superstructures that yield a self-supportive hydrogel at physiological pH. The material endures cell culture conditions and sustains fibroblast proliferation. Tripeptide superstructures are thoroughly analysed by several techniques.

Graphical abstract: Design of a hydrophobic tripeptide that self-assembles into amphiphilic superstructures forming a hydrogel biomaterial

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Article information


Submitted
24 Dec 2015
Accepted
15 Mar 2016
First published
15 Mar 2016

Chem. Commun., 2016,52, 5912-5915
Article type
Communication
Author version available

Design of a hydrophobic tripeptide that self-assembles into amphiphilic superstructures forming a hydrogel biomaterial

A. V. Vargiu, D. Iglesias, K. E. Styan, L. J. Waddington, C. D. Easton and S. Marchesan, Chem. Commun., 2016, 52, 5912
DOI: 10.1039/C5CC10531E

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