Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 35, 2016
Previous Article Next Article

Chemo- and regioselective reductive deoxygenation of 1-en-4-yn-ols into 1,4-enynes through FeF3 and TfOH co-catalysis

Author affiliations

Abstract

We report chemo- and regioselective direct reductive deoxygenation of 1-en-4-yn-3-ols into 1,4-enynes through FeF3 and TfOH cooperative catalysis under NBSH-mediated conditions. Further, we show the efficient synthesis of a pharmaceutically significant 1,4-enyne. The present methodology can also be used for chemo- and regioselective direct deoxygenation of other alcohols.

Graphical abstract: Chemo- and regioselective reductive deoxygenation of 1-en-4-yn-ols into 1,4-enynes through FeF3 and TfOH co-catalysis

Back to tab navigation

Supplementary files

Article information


Submitted
23 Dec 2015
Accepted
29 Mar 2016
First published
07 Apr 2016

Chem. Commun., 2016,52, 5936-5939
Article type
Communication

Chemo- and regioselective reductive deoxygenation of 1-en-4-yn-ols into 1,4-enynes through FeF3 and TfOH co-catalysis

Z. Yang, R. K. Kumar, P. Liao, Z. Liu, X. Li and X. Bi, Chem. Commun., 2016, 52, 5936
DOI: 10.1039/C5CC10518H

Social activity

Search articles by author

Spotlight

Advertisements