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Issue 19, 2016
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Crosslinked dendronized polyols as a general approach to brighter and more stable fluorophores

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Abstract

Fluorescent, aqueous-soluble, crosslinked dendronized polyols (CDPs) are obtained through a sequential process involving ring-opening metathesis polymerization (ROMP), intra-chain ring-closing metathesis (RCM), and hydrolysis. This general strategy improves the quantum yields (QYs), brightness, and photostability of five common fluorophores whose emission wavelengths cover 150 nm. Additionally, the availability of the polymeric fluorophore to the cytosomes opens the door to applications in bioimaging and intracellular delivery.

Graphical abstract: Crosslinked dendronized polyols as a general approach to brighter and more stable fluorophores

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Supplementary files

Article information


Submitted
13 Nov 2015
Accepted
01 Feb 2016
First published
01 Feb 2016

Chem. Commun., 2016,52, 3781-3784
Article type
Communication

Crosslinked dendronized polyols as a general approach to brighter and more stable fluorophores

Y. Li, Y. Bai, N. Zheng, Y. Liu, G. A. Vincil, B. J. Pedretti, J. Cheng and S. C. Zimmerman, Chem. Commun., 2016, 52, 3781
DOI: 10.1039/C5CC09430E

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