Issue 6, 2016
From the journal:

Chemical Communications

Phospha-fluorescein: a red-emissive fluorescein analogue with high photobleaching resistance†

Aiko Fukazawa,*a   Shinji Suda,a   Masayasu Taki,*b   Eriko Yamaguchi,a   Marek Grzybowski,b   Yoshikatsu Sato,b   Tetsuya Higashiyamabc  and  Shigehiro Yamaguchi*ab  

* Corresponding authors

a Department of Chemistry, Graduate School of Science, Nagoya University, Furo, Chikusa, Nagoya 464-8602, Japan
E-mail: yamaguchi@chem.nagoya-u.ac.jp

b Institute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University, Furo, Chikusa, Nagoya 464-8602, Japan

c Division of Biological Science, Graduate School of Science, Nagoya University, Furo, Chikusa, Nagoya 464-8602, Japan

Abstract

Phospha-fluorescein (POF), a phosphine oxide-containing analogue of fluorescein, was synthesized and its photophysical properties were examined. Compared with fluorescein and sila-fluorescein, POF displayed significantly red-shifted absorption and fluorescence as well as superior photobleaching resistance, while retaining the pH-responsive characteristics of fluorescein dyes.

Graphical abstract: Phospha-fluorescein: a red-emissive fluorescein analogue with high photobleaching resistance

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Article information

DOI
https://doi.org/10.1039/C5CC09345G
Article type
Communication
Submitted
11 Nov 2015
Accepted
20 Nov 2015
First published
30 Nov 2015

Chem. Commun., 2016,52, 1120-1123

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Phospha-fluorescein: a red-emissive fluorescein analogue with high photobleaching resistance

A. Fukazawa, S. Suda, M. Taki, E. Yamaguchi, M. Grzybowski, Y. Sato, T. Higashiyama and S. Yamaguchi, Chem. Commun., 2016, 52, 1120 DOI: 10.1039/C5CC09345G

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