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Issue 11, 2016
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A versatile water-soluble chelating and radical scavenging platform

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Abstract

The phenol-diamide compound, 5-(tert-butyl)-2-hydroxy-N1,N3-bis(2-hydroxyethyl)isophthalamide (1OH), is water-soluble, non-cytotoxic, and capable of both, trapping ROS species and chelating Cu(II) and Fe(III) ions; these combined properties confer a protective effect against ROS induced cell death.

Graphical abstract: A versatile water-soluble chelating and radical scavenging platform

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Submitted
05 Oct 2015
Accepted
15 Dec 2015
First published
21 Dec 2015

Chem. Commun., 2016,52, 2350-2353
Article type
Communication
Author version available

A versatile water-soluble chelating and radical scavenging platform

M. Eckshtain-Levi, R. Lavi, D. S. Yufit, B. Daniel, O. Green, O. Fleker, M. Richman, S. Rahimipour, A. Gruzman and L. Benisvy, Chem. Commun., 2016, 52, 2350
DOI: 10.1039/C5CC08198J

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