Issue 1, 2016
From the journal:

Chemical Communications

A water-stable metal–organic framework of a zwitterionic carboxylate with dysprosium: a sensing platform for Ebolavirus RNA sequences†

Liang Qin,a   Li-Xian Lin,a   Zhi-Ping Fang,a   Shui-Ping Yang,a   Gui-Hua Qiu,a   Jin-Xiang Chen*a  and  Wen-Hua Chen*a  

* Corresponding authors

a Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China
E-mail: jxchen@smu.edu.cn, whchen@smu.edu.cn

Abstract

We herein report a water-stable 3D dysprosium-based metal–organic framework (MOF) that can non-covalently interact with probe ss-DNA. The formed system can serve as an effective fluorescence sensing platform for the detection of complementary Ebolavirus RNA sequences with the detection limit of 160 pM.

Graphical abstract: A water-stable metal–organic framework of a zwitterionic carboxylate with dysprosium: a sensing platform for Ebolavirus RNA sequences

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Article information

DOI
https://doi.org/10.1039/C5CC06697B
Article type
Communication
Submitted
10 Aug 2015
Accepted
19 Oct 2015
First published
19 Oct 2015

Chem. Commun., 2016,52, 132-135

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A water-stable metal–organic framework of a zwitterionic carboxylate with dysprosium: a sensing platform for Ebolavirus RNA sequences

L. Qin, L. Lin, Z. Fang, S. Yang, G. Qiu, J. Chen and W. Chen, Chem. Commun., 2016, 52, 132 DOI: 10.1039/C5CC06697B

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