Fluorogenic nanoreactor assembly with boosted sensing kinetics for timely imaging of cellular hydrogen peroxide

Abstract

The precise detection of endogenous H₂O₂ has been considered to be a useful tool for understanding cell physiology. Here, we have developed a nanoreactor co-incorporated with a H₂O₂-responsive fluorogenic molecule and a catalytic additive. The fast sensing kinetics allows us to visualize a subcellular response in real-time.