Issue 1, 2016
From the journal:

Chemical Communications

Efficient and synergetic DNA delivery with pyridinium amphiphiles–gold nanoparticle composite systems having different packing parameters†

Adrian Kizewskia  and  Marc A. Ilies*bc  

* Corresponding authors

a College of Science and Technology, Temple University, 1803 N Broad Street, Philadelphia, PA-19122, USA

b Department of Pharmaceutical Sciences and Moulder Center of Drug Discovery Research, Temple University School of Pharmacy, 3307 N Broad Street, Philadelphia, PA-19140, USA
E-mail: mailies@temple.edu
Fax: +1-215-707-5620
Tel: +1-215-707-1749

c Temple Materials Institute, 1803 N Broad Street, Philadelphia, PA-19122, USA

Abstract

Mixtures of highly curved pyridinium-decorated Au nanoparticles and standard pyridinium cationic lipids efficiently and synergetically transfected DNA in vitro, while displaying an excellent cytotoxic profile.

Graphical abstract: Efficient and synergetic DNA delivery with pyridinium amphiphiles–gold nanoparticle composite systems having different packing parameters

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Article information

DOI
https://doi.org/10.1039/C5CC05760D
Article type
Feature Article
Submitted
12 Jul 2015
Accepted
06 Nov 2015
First published
06 Nov 2015

Chem. Commun., 2016,52, 60-63

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Efficient and synergetic DNA delivery with pyridinium amphiphiles–gold nanoparticle composite systems having different packing parameters

A. Kizewski and M. A. Ilies, Chem. Commun., 2016, 52, 60 DOI: 10.1039/C5CC05760D

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