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Issue 13, 2016

Signal enhancement in ligand–receptor interactions using dynamic polymers at quartz crystal microbalance sensors

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Abstract

The signal enhancement properties of QCM sensors based on dynamic, biotinylated poly(acrylic acid) brushes has been studied in interaction studies with an anti-biotin Fab fragment. The poly(acrylic acid) sensors showed a dramatic increase in signal response with more than ten times higher signal than the carboxyl-terminated self-assembled monolayer surface.

Graphical abstract: Signal enhancement in ligand–receptor interactions using dynamic polymers at quartz crystal microbalance sensors

Supplementary files

Article information


Submitted
29 Mar 2016
Accepted
11 May 2016
First published
12 May 2016

This article is Open Access

Analyst, 2016,141, 3993-3996
Article type
Communication

Signal enhancement in ligand–receptor interactions using dynamic polymers at quartz crystal microbalance sensors

G. Dunér, H. Anderson, Z. Pei, B. Ingemarsson, T. Aastrup and O. Ramström, Analyst, 2016, 141, 3993 DOI: 10.1039/C6AN00735J

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