Issue 8, 2016
From the journal:

Analyst

Fluorescence detection of telomerase activity in high concentration of cell lysates based on strand-displacement mediated recycling†

Xiaoqian Li,a   Wei Wang,a   Yaoyao Chena  and  Caifeng Ding*a  

* Corresponding authors

a Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P.R. China
E-mail: dingcaifeng2003@163.com

Abstract

Based on a template of the telomere elongation reaction of a telomerase substrate primer in the presence of telomerase, the strand-displacement process was used to prepare a fluorescence signal nanoprobe. An amplified fluorescence detection of telomerase activity in cancer cells is described in this manuscript.

Graphical abstract: Fluorescence detection of telomerase activity in high concentration of cell lysates based on strand-displacement mediated recycling

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Article information

DOI
https://doi.org/10.1039/C5AN02560E
Article type
Communication
Submitted
14 Dec 2015
Accepted
16 Mar 2016
First published
16 Mar 2016

Analyst, 2016,141, 2388-2391

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Fluorescence detection of telomerase activity in high concentration of cell lysates based on strand-displacement mediated recycling

X. Li, W. Wang, Y. Chen and C. Ding, Analyst, 2016, 141, 2388 DOI: 10.1039/C5AN02560E

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