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Issue 3, 2016

Biomarker detection technologies and future directions

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Abstract

Biomarkers play a vital role in disease detection and treatment follow-up. It is important to note that diseases in the early stage are typically treated with the greatest probability of success. However, due to various technical difficulties in current technologies for the detection of biomarkers, the potential of biomarkers is not explored completely. Therefore, the developments of technologies, which can enable the accurate detection of prostate cancer at an early stage with simple, experimental protocols are highly inevitable. This critical review evaluates the current methods and technologies used in the detection of biomarkers. The aim of this article is to provide a comprehensive review covering the advantages and disadvantages of the biomarker detection methods. Future directions for the development of technologies to achieve highly selective and sensitive detection of biomarkers for point-of-care applications are also commented on.

Graphical abstract: Biomarker detection technologies and future directions

Article information


Submitted
01 Sep 2015
Accepted
04 Nov 2015
First published
06 Nov 2015

This article is Open Access

Analyst, 2016,141, 740-755
Article type
Critical Review

Biomarker detection technologies and future directions

S. B. Nimse, M. D. Sonawane, K. Song and T. Kim, Analyst, 2016, 141, 740 DOI: 10.1039/C5AN01790D

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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