Issue 2, 2016
From the journal:

Analyst

A universal tumor cell isolation method enabled by fibrin-coated microchannels†

Jinling Zhanga  and  Z. Hugh Fan*abc  

* Corresponding authors

a Interdisciplinary Microsystems Group, Department of Mechanical and Aerospace Engineering, University of Florida, PO Box 116250, Gainesville, Florida 32611, USA
E-mail: hfan@ufl.edu
Fax: +1 352 392 7303
Tel: +1 352 846 3021

b J. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, P.O. Box 116131, Gainesville, FL 32611, USA

c Department of Chemistry, University of Florida, P.O. Box 117200, Gainesville, FL 32611, USA

Abstract

We report a simple but effective strategy to capture tumor cells using fibrin-immobilized microchannels. It is a universal method since it shows an ability to capture both epithelial and mesenchymal tumor cells. The cell capture efficiency is up to 90%.

Graphical abstract: A universal tumor cell isolation method enabled by fibrin-coated microchannels

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Article information

DOI
https://doi.org/10.1039/C5AN01783A
Article type
Communication
Submitted
31 Aug 2015
Accepted
04 Nov 2015
First published
06 Nov 2015

Analyst, 2016,141, 563-566

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A universal tumor cell isolation method enabled by fibrin-coated microchannels

J. Zhang and Z. H. Fan, Analyst, 2016, 141, 563 DOI: 10.1039/C5AN01783A

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