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Issue 1, 2016
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EM∩IM: software for relating ion mobility mass spectrometry and electron microscopy data

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Abstract

We present EM∩IM, software that allows the calculation of collision cross-sections from electron density maps obtained for example by means of transmission electron microscopy. This allows the assessment of structures other than those described by atomic coordinates with ion mobility mass spectrometry data, and provides a new means for contouring and validating electron density maps. EM∩IM thereby facilitates the use of data obtained in the gas phase within structural biology studies employing diverse experimental methodologies.

Graphical abstract: EM∩IM: software for relating ion mobility mass spectrometry and electron microscopy data

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Article information


Submitted
11 Aug 2015
Accepted
23 Nov 2015
First published
23 Nov 2015

Analyst, 2016,141, 70-75
Article type
Communication

EM∩IM: software for relating ion mobility mass spectrometry and electron microscopy data

M. T. Degiacomi and J. L. P. Benesch, Analyst, 2016, 141, 70
DOI: 10.1039/C5AN01636C

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