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Issue 2, 2016
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Microfluidics for research and applications in oncology

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Abstract

Cancer is currently one of the top non-communicable human diseases, and continual research and developmental efforts are being made to better understand and manage this disease. More recently, with the improved understanding in cancer biology as well as the advancements made in microtechnology and rapid prototyping, microfluidics is increasingly being explored and even validated for use in the detection, diagnosis and treatment of cancer. With inherent advantages such as small sample volume, high sensitivity and fast processing time, microfluidics is well-positioned to serve as a promising platform for applications in oncology. In this review, we look at the recent advances in the use of microfluidics, from basic research such as understanding cancer cell phenotypes as well as metastatic behaviors to applications such as the detection, diagnosis, prognosis and drug screening. We then conclude with a future outlook on this promising technology.

Graphical abstract: Microfluidics for research and applications in oncology

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Article information


Submitted
27 Feb 2015
Accepted
08 May 2015
First published
11 May 2015

Analyst, 2016,141, 504-524
Article type
Critical Review

Microfluidics for research and applications in oncology

P. K. Chaudhuri, M. Ebrahimi Warkiani, T. Jing, Kenry and C. T. Lim, Analyst, 2016, 141, 504
DOI: 10.1039/C5AN00382B

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