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Issue 34, 2016
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Facile green synthesis of calcium carbonate/folate porous hollow spheres for the targeted pH-responsive release of anticancer drugs

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Abstract

Biocompatible hybrid hollow spheres of calcium carbonate/folate with both mesopores and macropores were synthesized using a facile green approach based on Ostwald ripening. The porous hollow spheres were efficiently loaded with doxorubicin, which they were then able to release in a pH-responsive and sustained manner for the targeted treatment of human cancer cells.

Graphical abstract: Facile green synthesis of calcium carbonate/folate porous hollow spheres for the targeted pH-responsive release of anticancer drugs

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Publication details

The article was received on 16 Jun 2016, accepted on 24 Jul 2016 and first published on 25 Jul 2016


Article type: Communication
DOI: 10.1039/C6TB01483F
J. Mater. Chem. B, 2016,4, 5650-5653

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    Facile green synthesis of calcium carbonate/folate porous hollow spheres for the targeted pH-responsive release of anticancer drugs

    Y. Guo, W. Jia, H. Li, W. Shi, J. Zhang, J. Feng and L. Yang, J. Mater. Chem. B, 2016, 4, 5650
    DOI: 10.1039/C6TB01483F

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