Issue 12, 2016
From the journal:

Green Chemistry

Rapid production of benzazole derivatives by a high-pressure and high-temperature water microflow chemical process†

I. Nagao,*a   T. Ishizakaa  and  H. Kawanami*a  

* Corresponding authors

a Research Institute for Chemical Process Technology, Department of Materials and Chemistry, 4-2-1, Nigatake, Miyaginoku, Sendai 983-8551, Japan
E-mail: i.nagao@aist.go.jp, h-kawanami@aist.go.jp

Abstract

A high-pressure and high-temperature (HPHT) water microflow chemical process was utilized for the synthesis of benzazole derivatives. The current approach enables the extremely rapid production of various 2-arylbenzazoles including benzimidazoles, benzoxazoles, and benzthiazole in excellent yields.

Graphical abstract: Rapid production of benzazole derivatives by a high-pressure and high-temperature water microflow chemical process

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Article information

DOI
https://doi.org/10.1039/C6GC01195K
Article type
Communication
Submitted
28 Apr 2016
Accepted
16 May 2016
First published
25 May 2016
This article is Open Access
Creative Commons BY license

Green Chem., 2016,18, 3494-3498

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Rapid production of benzazole derivatives by a high-pressure and high-temperature water microflow chemical process

I. Nagao, T. Ishizaka and H. Kawanami, Green Chem., 2016, 18, 3494 DOI: 10.1039/C6GC01195K

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