Jump to main content
Jump to site search

Issue 9, 2016
Previous Article Next Article

The effect of sun-dried raisins (Vitis vinifera L.) on the in vitro composition of the gut microbiota

Author affiliations

Abstract

Modulation of the human gut microbiota has proven to have beneficial effects on host health. The aim of this work was to evaluate the effect of sun-dried raisins (SR) on the composition of the human gut microbiota. A full model of the gastrointestinal tract, which includes simulated mastication, a dynamic gastric model, a duodenal model and a colonic model of the human large intestine, was used. An increase in the numbers of bifidobacteria and lactobacilli was observed by plate-counting in response to the addition of either SR or FOS after 8 and 24 h fermentation. A significant decrease in Firmicutes and Bacteroidetes was observed in SR samples after 8 and 24 h fermentation. FOS resulted in the greatest production of short chain fatty acids. Sun-dried raisins demonstrated considerable potential to promote the colonization and proliferation of beneficial bacteria in the human large intestine and to stimulate the production of organic acids.

Graphical abstract: The effect of sun-dried raisins (Vitis vinifera L.) on the in vitro composition of the gut microbiota

Back to tab navigation

Supplementary files

Article information


Submitted
30 Jul 2016
Accepted
13 Aug 2016
First published
16 Aug 2016

This article is Open Access

Food Funct., 2016,7, 4048-4060
Article type
Paper

The effect of sun-dried raisins (Vitis vinifera L.) on the in vitro composition of the gut microbiota

G. Mandalari, S. Chessa, C. Bisignano, L. Chan and A. Carughi, Food Funct., 2016, 7, 4048
DOI: 10.1039/C6FO01137C

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Material from this article can be used in other publications provided that the correct acknowledgement is given with the reproduced material.

Reproduced material should be attributed as follows:

  • For reproduction of material from NJC:
    [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the Centre National de la Recherche Scientifique (CNRS) and the RSC.
  • For reproduction of material from PCCP:
    [Original citation] - Published by the PCCP Owner Societies.
  • For reproduction of material from PPS:
    [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC.
  • For reproduction of material from all other RSC journals:
    [Original citation] - Published by The Royal Society of Chemistry.

Information about reproducing material from RSC articles with different licences is available on our Permission Requests page.


Social activity

Search articles by author

Spotlight

Advertisements