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Issue 6, 2016
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A novel polysaccharide isolated from mulberry fruits (Murus alba L.) and its selenide derivative: structural characterization and biological activities

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Abstract

A novel polysaccharide (MFP3P) was isolated from Murus alba L. through the hot water extraction method followed by chromatographic purification. The chemical structure of MFP3P was elucidated by acid hydrolysis, Smith degradation and methylation analysis, along with FT-IR, GC-MS, 1H and 13C NMR spectroscopy. Its morphological properties were further characterized by SEM and AFM. The selenide of the polysaccharide (MFP3P-Se) was obtained by the Na2SeO3/BaCl2 method. The antioxidant properties showed that MFP3P-Se exhibited higher peroxy radical-scavenging capacity than MFP3P in vitro. Moreover, MFP3P-Se had more significant hypoglycemic effects than MFP3P through promoting pancreatic cell proliferation and increasing glucose metabolism and insulin secretion.

Graphical abstract: A novel polysaccharide isolated from mulberry fruits (Murus alba L.) and its selenide derivative: structural characterization and biological activities

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Publication details

The article was received on 16 Mar 2016, accepted on 19 May 2016 and first published on 20 May 2016


Article type: Paper
DOI: 10.1039/C6FO00370B
Food Funct., 2016,7, 2886-2897

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    A novel polysaccharide isolated from mulberry fruits (Murus alba L.) and its selenide derivative: structural characterization and biological activities

    C. Chen, B. Zhang, X. Fu and R. H. Liu, Food Funct., 2016, 7, 2886
    DOI: 10.1039/C6FO00370B

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