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Issue 83, 2016
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Boronate based fluorescence (ESIPT) probe for peroxynitrite

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Abstract

A simple probe for the detection of peroxynitrite was developed incorporating a benzyl boronic ester “protecting” unit. The “protecting” unit of the probe is removed by peroxynitrite to “turn-on” ESIPT fluorescence (4.5 fold enhancement). Furthermore, the probe was cell permeable and was used in cell imaging experiments showing an off–on response towards peroxynitrite, in HeLa and RAW 264.7 cells.

Graphical abstract: Boronate based fluorescence (ESIPT) probe for peroxynitrite

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Submitted
19 Aug 2016
Accepted
19 Sep 2016
First published
19 Sep 2016

This article is Open Access

Chem. Commun., 2016,52, 12350-12352
Article type
Communication

Boronate based fluorescence (ESIPT) probe for peroxynitrite

A. C. Sedgwick, X. Sun, G. Kim, J. Yoon, S. D. Bull and T. D. James, Chem. Commun., 2016, 52, 12350
DOI: 10.1039/C6CC06829D

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