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Issue 75, 2016
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A biotin-guided formaldehyde sensor selectively detecting endogenous concentrations in cancerous cells and tissues

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Abstract

A biotin appended formaldehyde sensor was found to specifically visualise both exogenous and endogenous levels of formaldehyde in biotin receptor positive cells over biotin negative cells by means of one- and two-photon excitation. The probe furthermore visualised endogenous levels of formaldehyde in tumour tissue slices up to 70 μm depth.

Graphical abstract: A biotin-guided formaldehyde sensor selectively detecting endogenous concentrations in cancerous cells and tissues

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Supplementary files

Article information


Submitted
26 Jul 2016
Accepted
17 Aug 2016
First published
17 Aug 2016

Chem. Commun., 2016,52, 11247-11250
Article type
Communication

A biotin-guided formaldehyde sensor selectively detecting endogenous concentrations in cancerous cells and tissues

Y. H. Lee, Y. Tang, P. Verwilst, W. Lin and J. S. Kim, Chem. Commun., 2016, 52, 11247
DOI: 10.1039/C6CC06158C

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