Issue 40, 2016

A de novo self-assembling peptide hydrogel biosensor with covalently immobilised DNA-recognising motifs

Abstract

We report here the first experimental evidence of a self-assembling three-dimensional (3D) peptide hydrogel, with recognition motifs immobilized on the surface of fibres capable of sequence-specific oligonucleotide detection. These systems have the potential to be further developed into diagnostic and prognostic tools in human pathophysiology.

Graphical abstract: A de novo self-assembling peptide hydrogel biosensor with covalently immobilised DNA-recognising motifs

Supplementary files

Article information

Article type
Communication
Submitted
16 Feb 2016
Accepted
18 Apr 2016
First published
19 Apr 2016
This article is Open Access
Creative Commons BY license

Chem. Commun., 2016,52, 6697-6700

Author version available

A de novo self-assembling peptide hydrogel biosensor with covalently immobilised DNA-recognising motifs

P. J. S. King, A. Saiani, E. V. Bichenkova and A. F. Miller, Chem. Commun., 2016, 52, 6697 DOI: 10.1039/C6CC01433J

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