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Issue 29, 2016
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An enzyme-responsive controlled release system based on a dual-functional peptide

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Abstract

A new controlled release system was developed by loading a dual-functional peptide (DFP) on a mesoporous silica material. One-pot synthesis produced a DFP that was stimuli responsive, releasing a therapeutic peptide by protease cleavage. The design provides new steps towards smart biomaterials.

Graphical abstract: An enzyme-responsive controlled release system based on a dual-functional peptide

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Article information


Submitted
22 Dec 2015
Accepted
14 Mar 2016
First published
14 Mar 2016

Chem. Commun., 2016,52, 5112-5115
Article type
Communication

An enzyme-responsive controlled release system based on a dual-functional peptide

X. Li, S. Burger, A. J. O'Connor, L. Ong, J. A. Karas and S. L. Gras, Chem. Commun., 2016, 52, 5112
DOI: 10.1039/C5CC10480G

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