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Issue 17, 2016
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Drug–drug co-crystallization presents a new opportunity for the development of stable vitamins

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Abstract

Drug–drug co-crystallization could realize combination drugs at a molecular level. Two polymorphic co-crystals between VD2 and VD3 were successfully designed and synthesized. These enantiotropic polymorphs exhibit significantly different physicochemical stabilities.

Graphical abstract: Drug–drug co-crystallization presents a new opportunity for the development of stable vitamins

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Publication details

The article was received on 16 Dec 2015, accepted on 27 Jan 2016 and first published on 27 Jan 2016


Article type: Communication
DOI: 10.1039/C5CC10297A
Chem. Commun., 2016,52, 3572-3575

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    Drug–drug co-crystallization presents a new opportunity for the development of stable vitamins

    J. Wang, Q. Yu, W. Dai and X. Mei, Chem. Commun., 2016, 52, 3572
    DOI: 10.1039/C5CC10297A

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