Transforming the recognition site of 4-hydroxyaniline into 4-methoxyaniline grafted onto a BODIPY core switches the selective detection of peroxynitrite to hypochlorous acid

Chunchang Zhao; Jiancai An; Li Zhou; Qiang Fei; Feiyi Wang; Jie Tan; Ben Shi; Rui Wang; Zhiqian Guo; Wei-Hong Zhu

doi:10.1039/C5CC08936K

Transforming the recognition site of 4-hydroxyaniline into 4-methoxyaniline grafted onto a BODIPY core switches the selective detection of peroxynitrite to hypochlorous acid†

Chunchang Zhao,*^a Jiancai An,‡^a Li Zhou,‡^b Qiang Fei,^a Feiyi Wang,^a Jie Tan,^a Ben Shi,^a Rui Wang,*^b Zhiqian Guo^a and Wei-Hong Zhu^a

Author affiliations

* Corresponding authors

^a Key Laboratory for Advanced Materials and Institute of Fine Chemicals, East China University of Science & Technology, Shanghai 200237, P. R. China
E-mail: zhaocchang@ecust.edu.cn

^b Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science & Technology, Shanghai 200237, P. R. China
E-mail: ruiwang@ecust.edu.cn

Abstract

Two novel probes were designed, sharing the same BODIPY core but differing only by a minimized variation in the recognition site from 4-hydroxyaniline into 4-methoxyaniline. Such a small change in the reaction site could switch the selective detection from peroxynitrite to HOCl. Undoubtedly, the new designed BODIPY core exhibits valuable properties.

Chemical Communications

Transforming the recognition site of 4-hydroxyaniline into 4-methoxyaniline grafted onto a BODIPY core switches the selective detection of peroxynitrite to hypochlorous acid†

Abstract

Supplementary files

Article information

Download Citation

Permissions

Transforming the recognition site of 4-hydroxyaniline into 4-methoxyaniline grafted onto a BODIPY core switches the selective detection of peroxynitrite to hypochlorous acid

Social activity

Search articles by author

Spotlight

Advertisements