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Issue 35, 2015
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Virus-inspired mimics: self-assembly of dendritic lipopeptides into arginine-rich nanovectors for improving gene delivery

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Abstract

With inspirations from natural viruses, arginine-containing dendritic lipopeptides were designed for bioinspired fabrication. Self-assembling the defined amphiphilic lipopeptides generated virus-inspired nanovectors with an arginine-rich corona. These nanovectors provided some remarkable benefits for gene delivery, including well-defined nanostructure, high transfection efficiency, serum resistance and low cytotoxicity.

Graphical abstract: Virus-inspired mimics: self-assembly of dendritic lipopeptides into arginine-rich nanovectors for improving gene delivery

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Publication details

The article was received on 03 Jun 2015, accepted on 27 Jul 2015 and first published on 28 Jul 2015


Article type: Communication
DOI: 10.1039/C5TB01070E
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J. Mater. Chem. B, 2015,3, 7006-7010

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    Virus-inspired mimics: self-assembly of dendritic lipopeptides into arginine-rich nanovectors for improving gene delivery

    X. Xu, Q. Jiang, X. Zhang, Y. Nie, Z. Zhang, Y. Li, G. Cheng and Z. Gu, J. Mater. Chem. B, 2015, 3, 7006
    DOI: 10.1039/C5TB01070E

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