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Issue 20, 2015
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An overview of the suitability of hydrogel-forming polymers for extrusion-based 3D-printing

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Abstract

This review evaluates hydrogel-forming polymers that are suitable for soft tissue engineering with a focus on materials that can be fabricated using additive manufacturing (3D-printing). An overview of the specific material requirements for hydrogel-based tissue engineering constructs is presented. This is followed by an explanation of the various hydrogel-forming polymer classes that includes a detailed examination of material properties that are critical for extrusion printing. Specifically, mechanisms for hydrogel formation, degradation, and biological response, activity and compatibility are explored. A discussion of extrusion printing strategies for printable hydrogel-forming polymers is then presented in conjunction with a list of considerations to guide future tissue engineering developments.

Graphical abstract: An overview of the suitability of hydrogel-forming polymers for extrusion-based 3D-printing

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Publication details

The article was received on 28 Feb 2015, accepted on 28 Apr 2015 and first published on 29 Apr 2015


Article type: Review Article
DOI: 10.1039/C5TB00393H
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J. Mater. Chem. B, 2015,3, 4105-4117

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    An overview of the suitability of hydrogel-forming polymers for extrusion-based 3D-printing

    D. M. Kirchmajer, R. Gorkin III and M. in het Panhuis, J. Mater. Chem. B, 2015, 3, 4105
    DOI: 10.1039/C5TB00393H

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