Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance work on Wednesday 22nd May 2019 from 11:00 AM to 1:00 PM (GMT).

During this time our website performance may be temporarily affected. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 16, 2015
Previous Article Next Article

Design and synthesis of fluorenone-based dyes: two-photon excited fluorescent probes for imaging of lysosomes and mitochondria in living cells

Author affiliations

Abstract

Three fluorenone-derived two-photon fluorescent probes (TK) targeting the lysosomes (TK-Lyso) and mitochondria (TK-Mito1 and TK-Mito2) were synthesized by introducing different diphenylamine moieties into the fluorenone core. The TK dyes showed high biocompatibility and long-term retention, low cytotoxicity, large Stokes shift and good fluorescence quantum yield. The results of the present work disclose a class of organic dyes with potential wide applications as specific and efficient probes for lysosomes and mitochondria in the study of various biological processes.

Graphical abstract: Design and synthesis of fluorenone-based dyes: two-photon excited fluorescent probes for imaging of lysosomes and mitochondria in living cells

Back to tab navigation

Supplementary files

Publication details

The article was received on 22 Dec 2014, accepted on 04 Mar 2015 and first published on 04 Mar 2015


Article type: Paper
DOI: 10.1039/C4TB02116A
Author version
available:
Download author version (PDF)
J. Mater. Chem. B, 2015,3, 3315-3323

  •   Request permissions

    Design and synthesis of fluorenone-based dyes: two-photon excited fluorescent probes for imaging of lysosomes and mitochondria in living cells

    A. L. Capodilupo, V. Vergaro, E. Fabiano, M. De Giorgi, F. Baldassarre, A. Cardone, A. Maggiore, V. Maiorano, D. Sanvitto, G. Gigli and G. Ciccarella, J. Mater. Chem. B, 2015, 3, 3315
    DOI: 10.1039/C4TB02116A

Search articles by author

Spotlight

Advertisements