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Issue 7, 2015
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The evolution of fibrin-specific targeting strategies

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Abstract

Fibrin-specific targeting capabilities have been highly sought for over 50 years due to their implications for bio-molecule delivery, diagnostics, and regenerative medicine. Yet only recently has our full knowledge of fibrin's complex polymerization dynamics and biological interactions begun to be fully exploited in pursuit of this goal. This highlight will discuss the range of rapidly changing strategies for specifically targeting fibrin over the precursor fibrinogen and the advantages and disadvantages of these approaches for various applications.

Graphical abstract: The evolution of fibrin-specific targeting strategies

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Publication details

The article was received on 24 Oct 2014, accepted on 08 Jan 2015 and first published on 13 Jan 2015


Article type: Highlight
DOI: 10.1039/C4TB01769B
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J. Mater. Chem. B, 2015,3, 1177-1186

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    The evolution of fibrin-specific targeting strategies

    V. L. Stefanelli and T. H. Barker, J. Mater. Chem. B, 2015, 3, 1177
    DOI: 10.1039/C4TB01769B

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