Hyaluronan/Ru(ii)-cyclodextrin supramolecular assemblies for colorimetric sensor of hyaluronidase activity†
Abstract
A hyaluronidase (HAase)-induced colorimetric change was found in a solution of a supramolecular assembly constructed from hyaluronan (HA) and a cationic Ru(II)-cyclodextrin complex under laser (532 nm) irradiation. The colorimetric change would be due to the relative intensities of scattered light from the assembly and the fluorescence of the Ru(II) complex.