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Issue 90, 2015
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Synthesis of new chiral lactam-fused pyridine derivatives

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Abstract

New chiral C2-symmetric and unsymmetric lactam-fused pyridines have been synthesised in enantiomerically pure forms with satisfactory yields via an acid-promoted cyclisation of benzylidene-modified tetramic acids and various enamines.

Graphical abstract: Synthesis of new chiral lactam-fused pyridine derivatives

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Publication details

The article was received on 29 Jul 2015, accepted on 24 Aug 2015 and first published on 25 Aug 2015


Article type: Communication
DOI: 10.1039/C5RA16896A
RSC Adv., 2015,5, 73562-73565

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    Synthesis of new chiral lactam-fused pyridine derivatives

    T. Sengoku, Y. Murata, C. Suzuki, M. Takahashi and H. Yoda, RSC Adv., 2015, 5, 73562
    DOI: 10.1039/C5RA16896A

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