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Issue 63, 2015
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Rational design of a fluopyram hapten and preparation of bioconjugates and antibodies for immunoanalysis

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Abstract

A fluopyram hapten was designed in which insignificant electronic and structural modifications were foreseen and all potentially interacting chemical moieties were maintained. This hapten was prepared by total synthesis and three immunologically active bioconjugates were obtained and characterized. High-affinity and specific antibodies to fluopyram were raised.

Graphical abstract: Rational design of a fluopyram hapten and preparation of bioconjugates and antibodies for immunoanalysis

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Supplementary files

Article information


Submitted
15 May 2015
Accepted
03 Jun 2015
First published
03 Jun 2015

This article is Open Access

RSC Adv., 2015,5, 51337-51341
Article type
Communication
Author version available

Rational design of a fluopyram hapten and preparation of bioconjugates and antibodies for immunoanalysis

E. Ceballos-Alcantarilla, C. Agulló, A. Abad-Fuentes, A. Abad-Somovilla and J. V. Mercader, RSC Adv., 2015, 5, 51337
DOI: 10.1039/C5RA09124A

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