Issue 63, 2015
From the journal:

RSC Advances

Rational design of a fluopyram hapten and preparation of bioconjugates and antibodies for immunoanalysis†

E. Ceballos-Alcantarilla,a   C. Agulló,a   A. Abad-Fuentes,b   A. Abad-Somovilla*a  and  J. V. Mercader*b  

* Corresponding authors

a Department of Organic Chemistry, Universitat de València, Doctor Moliner 50, Burjassot, València, Spain
E-mail: antonio.abad@uv.es

b Department of Biotechnology, Institute of Agrochemistry and Food Technology, Consejo Superior de Investigaciones Científicas (IATA–CSIC), Agustí Escardino 7, Paterna, València, Spain
E-mail: jvmercader@iata.csic.es

Abstract

A fluopyram hapten was designed in which insignificant electronic and structural modifications were foreseen and all potentially interacting chemical moieties were maintained. This hapten was prepared by total synthesis and three immunologically active bioconjugates were obtained and characterized. High-affinity and specific antibodies to fluopyram were raised.

Graphical abstract: Rational design of a fluopyram hapten and preparation of bioconjugates and antibodies for immunoanalysis

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C5RA09124A
Article type
Communication
Submitted
15 May 2015
Accepted
03 Jun 2015
First published
03 Jun 2015
This article is Open Access
Creative Commons BY license

RSC Adv., 2015,5, 51337-51341

Author version available

Download author version (PDF)

Permissions

Request permissions

Rational design of a fluopyram hapten and preparation of bioconjugates and antibodies for immunoanalysis

E. Ceballos-Alcantarilla, C. Agulló, A. Abad-Fuentes, A. Abad-Somovilla and J. V. Mercader, RSC Adv., 2015, 5, 51337 DOI: 10.1039/C5RA09124A

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements