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Issue 58, 2015
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Metal free one-pot synthesis of α-ketoamides from terminal alkenes

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Abstract

A practical approach towards the synthesis of α-ketoamides from readily available terminal alkenes (styrenes) has been developed. Use of inexpensive I2/2-iodoxybenzoic acid (IBX) in dimethyl sulphoxide (DMSO) as an oxidant under metal free one-pot conditions makes this methodology versatile.

Graphical abstract: Metal free one-pot synthesis of α-ketoamides from terminal alkenes

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Supplementary files

Article information


Submitted
31 Mar 2015
Accepted
15 May 2015
First published
15 May 2015

RSC Adv., 2015,5, 47265-47269
Article type
Paper
Author version available

Metal free one-pot synthesis of α-ketoamides from terminal alkenes

S. Dutta, S. S. Kotha and G. Sekar, RSC Adv., 2015, 5, 47265
DOI: 10.1039/C5RA05671C

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