Issue 41, 2015

Synthesis of polysubstituted 4-aminopyrazoles and 4-hydroxypyrazoles from vinyl azides and hydrazines

Abstract

A simple and direct synthesis of polysubstituted 4-aminopyrazoles and 4-hydroxypyrazoles from vinyl azides and hydrazines was developed. The present reactions were performed under mild conditions in moderate to excellent yields. A possible mechanism is also proposed.

Graphical abstract: Synthesis of polysubstituted 4-aminopyrazoles and 4-hydroxypyrazoles from vinyl azides and hydrazines

Supplementary files

Article information

Article type
Paper
Submitted
12 Mar 2015
Accepted
25 Mar 2015
First published
26 Mar 2015

RSC Adv., 2015,5, 32740-32743

Synthesis of polysubstituted 4-aminopyrazoles and 4-hydroxypyrazoles from vinyl azides and hydrazines

W. Huang, S. Liu, B. Chen, X. Guo and Y. Yu, RSC Adv., 2015, 5, 32740 DOI: 10.1039/C5RA04371A

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