Issue 42, 2015

A sequential synthetic strategy towards unexplored dibenzo[b,f][1,4]thiazepine carboxamides: copper catalysed C–S cyclisation followed by Ugi type 3CC cascade

Abstract

A two-step diversity oriented synthetic protocol to a novel class of dihydrodibenzo[b,f][1,4]thiazepine-11-carboxamides has been developed. The first step ensures the synthesis of dibenzothiazepine via copper-mediated condition followed by Ugi–Joullié reaction of the resultant cyclic imine in the second step.

Graphical abstract: A sequential synthetic strategy towards unexplored dibenzo[b,f][1,4]thiazepine carboxamides: copper catalysed C–S cyclisation followed by Ugi type 3CC cascade

Supplementary files

Article information

Article type
Paper
Submitted
09 Mar 2015
Accepted
02 Apr 2015
First published
02 Apr 2015

RSC Adv., 2015,5, 33067-33076

Author version available

A sequential synthetic strategy towards unexplored dibenzo[b,f][1,4]thiazepine carboxamides: copper catalysed C–S cyclisation followed by Ugi type 3CC cascade

D. Saha, P. Wadhwa and A. Sharma, RSC Adv., 2015, 5, 33067 DOI: 10.1039/C5RA04175A

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