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Issue 37, 2015
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A biocompatible process to prepare hyaluronan-based material able to self-assemble into stable nano-particles

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Abstract

New self-assembled nano-particles were developed by chemical conjugation of natural fatty acids to the backbone of hyaluronan (HA). The chemical structure and the self-association behavior of them were studied by FT-IR, NMR, fluorescence and dynamic light scattering. The HA derivatives form stable spherical shape aggregates, as assessed by transmission electron microscopy.

Graphical abstract: A biocompatible process to prepare hyaluronan-based material able to self-assemble into stable nano-particles

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Publication details

The article was received on 18 Feb 2015, accepted on 20 Mar 2015 and first published on 20 Mar 2015


Article type: Communication
DOI: 10.1039/C5RA03107A
Citation: RSC Adv., 2015,5, 29573-29576

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    A biocompatible process to prepare hyaluronan-based material able to self-assemble into stable nano-particles

    E. Calce, P. Ringhieri, F. A. Mercurio, M. Leone, V. Bugatti, M. Saviano, V. Vittoria and S. De Luca, RSC Adv., 2015, 5, 29573
    DOI: 10.1039/C5RA03107A

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