Antibacterial activities of TiO2 nanotubes on Porphyromonas gingivalis
Titanium-based nanomaterials have been widely used as dental implants because of their beneficial antiseptic and nano-interfacial effects. In particular, their application as surface decontamination biocompatible materials attracts increasing attention. In this study, a TiO2 nanotube-based antibacterial system has been fabricated by an anodic oxidation method, and its morphology, crystalline phase and hydrophilic property have been characterized. The effects of TiO2 nanotubes on bacterial growth inhibition, as well as bacterial cell fate, were also investigated. The results indicated that mixed-phase TiO2 nanotubes show excellent antibacterial performance under ultraviolet light irradiation, and their antibacterial ability could be attributed to the oxidative stress induced by the TiO2 nanotubes. The antibacterial performance of the TiO2 nanotube coating can be manipulated by photocatalytic activity as well as geometrical characteristics. Our study is the first to reveal the interactions of TiO2 surface that may increase the potential survival chances of Porphyromonas gingivalis when exposed to an antibacterial drug.