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Issue 5, 2015
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Zirconocene dichloride catalysed one-pot synthesis of pyrroles through nitroalkene-enamine assembly

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Abstract

Zirconocene dichloride in an environment-friendly ethanol medium was found to be an efficient catalyst for the synthesis of multi-substituted pyrroles by involving multi-component reactions of amines, β-dicarbonyl compounds and nitroalkenes. The reactions undergo completion easily with high yields and no side-products, allowing the purification of pyrroles in hassle-free and economical manner.

Graphical abstract: Zirconocene dichloride catalysed one-pot synthesis of pyrroles through nitroalkene-enamine assembly

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Publication details

The article was received on 05 Sep 2014, accepted on 12 Nov 2014 and first published on 10 Dec 2014


Article type: Paper
DOI: 10.1039/C4RA09873K
RSC Adv., 2015,5, 3187-3195

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    Zirconocene dichloride catalysed one-pot synthesis of pyrroles through nitroalkene-enamine assembly

    S. Goyal, J. K. Patel, M. Gangar, K. Kumar and V. A. Nair, RSC Adv., 2015, 5, 3187
    DOI: 10.1039/C4RA09873K

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