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Issue 7, 2015
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A challenging Heck reaction of maleimides

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Abstract

Maleimides are extremely susceptible to basic hydrolysis and gave poor yields under Heck conditions. The longstanding problem is solved with the use of a weak base KOAc in a carbonate solvent.

Graphical abstract: A challenging Heck reaction of maleimides

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Supplementary files

Article information


Submitted
13 Jan 2015
Accepted
15 Apr 2015
First published
16 Apr 2015

Org. Chem. Front., 2015,2, 775-777
Article type
Research Article
Author version available

A challenging Heck reaction of maleimides

L. H. Lim and J. (. Zhou, Org. Chem. Front., 2015, 2, 775
DOI: 10.1039/C5QO00015G

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