Lilong Gao, Guangyu Zha, Ying Wang, Qiaojie Luo, Weipu Zhu, Zhiquan Shen and Xiaodong Li
Polym. Chem., 2015,6, 8240-8243
DOI:
10.1039/C5PY01383F,
Communication
We developed a facile strategy to prepare an injectable drug-loaded hydrogel with chemical crosslinkages. A PCL-POEGM-PCL amphiphilic triblock copolymer was synthesized in “one pot” by a combination of polycondensation and ring-opening polymerization, which can disperse hydrophobic drugs in aqueous solution and be crosslinked by POEGMS under physiological conditions.